UJI EFEKTIVITAS ANTIBAKTERI SEDIAAN SABUN PADAT TRANSPARAN EKSTRAK ETANOL DAUN CABE RAWIT (Capsicum Frutescens L.) TERHADAP BAKTERI Propionibacterium acne
Abstract
Cayenne pepper leaves (Capsicum frutescens L.) can traditionally be used as an alternative treatment for acne from natural ingredients. This study aims to determine the effectiveness and concentration of the transparent solid soap formulation ethanol extract of cayenne pepper (Capsicum frustescens L.) leaves in inhibiting the growth of acne-causing bacteria (Propionibacterium acne). The method used in this research is experimental. Making cayenne pepper leaf extract (Capsicum Frutescens L.) by maceration method using 96% ethanol then making a transparent solid soap formulation and testing the effectiveness of antibacterial using disc paper diffusion method against Propionibacterium acnes bacteria by measuring the diameter of the inhibition zone for bacterial growth so that it can known Minimum Inhibitory Concentration (MIC). The concentration of Cayenne pepper leaf extract and the transparent solid soap formula used were (FI) 1%; (FII) 2%; (FIII) 3% and blanks (K+) Ranee soap and (K-) extractless soap. Evaluation of the physical quality of transparent solid soap preparations includes: organoleptic test, pH test, foam power test. From the test results, the average transparent solid soap preparation with a concentration of 1% produced an inhibition zone of 10.7 mm, a concentration of 2% produced an inhibition zone of 11.8 mm, and a concentration of 3% produced an inhibition zone of 12.6 mm. Minimum Inhibitory concentration (MIC) which produced the best ethanol extract of cayenne pepper (Capsicum frutescens L.) leaves was found at a concentration of 1% with a Width of Inhibitory Power (LDH) of 10.7 mm. The One Way Anova test obtained a significance value of 0.000 <0.05, so the results were significant, so there were significant differences between treatments. This means that the use of cayenne pepper leaf extract (Capsicum frutescens L.) has an effect on the growth of Propionibacterium acnes bacteria.
References
DepKes RI. (1995). Materia Medika Indonesia (IV). Jilid VI.
DepKes RI. (2000). Parameter Standar Umum Ekstrak Tumbuhan Obat.
Dewitasari, W. F., & Yuliastrin, A. (2019). Aktivitas Antibakteri Ekstrak Etanol Daun Cabe Rawit Putih (Capsicum frutescens L). Proceeding Biology Education Conference, 16(1), 295–301.
Djajadisastra, J., Mun, A., & Joshita Djajadisastra, P. (2009). FORMULASI GEL TOPIKAL DARI EKSTRAK NERII FOLIUM DALAM SEDIAAN ANTI JERAWAT*. In Jurnal Farmasi Indonesia (Vol. 4, Issue 4).
Hardianty Anuzar, C., Hazar, S., Farmasi, P., & Matematika dan Ilmu Pengetahuan Alam, F. (2017). Prosiding Farmasi Uji Aktivitas Antibakteri Ekstrak Etanol Daun Cabe Rawit (Capsicum frustescens L.) terhadap Pertumbuhan Bakteri Penyebab Jerawat Propionibacterium acnes secara Invitro.
Komala, O., Andini, S., & Zahra, F. (2020). UJI AKTIVITAS ANTIBAKTERI SABUN WAJAH EKSTRAK DAUN BELUNTAS (Pluchea indica L.) TERHADAP Propionibacterium acnes. FITOFARMAKA: Jurnal Ilmiah Farmasi, 10(1), 12–21. https://doi.org/10.33751/jf.v10i1.1717
Pahala, R., Gultom, J., & Siagian, H. S. (2021.). Uji Aktivitas Analgetik Fraksi Aktif Ekstrak Metanol Daun Dewa (Gynura pseudochina (L.) DC.) Terhadap Mencit Jantan (Mus musculus). In Jurnal Farmasi Higea (Vol. 13, Issue 2).
Pramushinta, I. A. K., & Ajiningrum, P. S. (2018). FORMULASI SEDIAAN SABUN PADAT TRANSPARAN DENGAN PENAMBAHAN EKSTRAK BIJI BUNGA MATAHARI (Helianthus annus L.). In Stigma (Vol. 11, Issue 1).
Rodiah, Nengah Kundera, I., & Binti Non Shamdas, G. (2017). Efektivitas Antibakteri Ekstrak Daun Cabai Rawit (Capsicum Frutescen L.) Terhadap Pertumbuhan Bakteri Propionibacterium Acnes dan Implementasinya Sebagai Media Pembelajaran Anti-Bakteria Affectivity Of Cayenne Pepper (Capsicum frutescen L.) Extract On Bac. In JIP BIOL (Vol. 5, Issue 1).
SNI. (1996). Standar Mutu Sabun Mandi Cair. National Standardization Agency of Indonesia, 1–15.
Susanty, E., Program, S., Farmasi, S., & Biologi, J. (2014). SKRINING FITOKIMIA EKSTRAK ETANOL DAUN GATAL (Laportea decumana (Roxb.) Wedd). 11(01).
Wardania, A. K., Malfadinata, S., & Fitriana, Y. (2020). Uji Aktivitas Antibakteri Penyebab Jerawat Staphylococcus epidermidis Menggunakan Ekstrak Daun Ashitaba (Angelica keiskei). Lumbung Farmasi: Jurnal Ilmu Kefarmasian, 1(1), 14. https://doi.org/10.31764/lf.v1i1.1206
Yulyuswarni, Y., & Mulatasih, E. R. (2021). Formulasi dan Evaluasi Sabun Padat Transparant Ekstrak Frezzed Drying Kayu Secang (Caesalpinia Sappan L) Sebagai Sabun Anti Jerawat. Jurnal Sains Dan Kesehatan, 3(4), 531–537. https://doi.org/10.25026/jsk.v3i4.464
Yunita. (2012). Uji aktivitas antioksidan ekstrak dan fraksi ekstrak daun cabe rawit ( capsicum frutescens L .) dan identifikasi golongan senyawa dari fraksi teraktif = Antioxidant activity test of hot short pepper leaves ( capsicum frutescens L .) extracts and extract f. 1–2.
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