EVALUASI INTERAKSI OBAT JANTUNG KORONER PADA PASIEN RAWAT INAP DI RUMAH SAKIT UMUM IMELDA PEKERJA INDONESIA MEDAN
Abstract
Coronary heart disease is the most common cause of death globally. Deaths in patients with coronary heart disease are 7.8 million out of 11.11 million people in developing countries in 2020. One of the factors that can worsen heart disease is drug interactions caused by patients with heart disease not only having one disease but followed by other diseases. so that they use more than one kind of drug. The purpose of this study was to describe the treatment profile of CHD patients and drug interactions in coronary heart inpatients at Imelda General Hospital, Indonesian Workers. This research is an observational study designed with retrospective descriptive design. Data analysis was carried out by screening drug interactions using the Drug Interaction Checker. The results showed that the criteria for CHD patients mostly occurred in women (56.3%) at the age of 56-60 years (23.9%). The distribution of diagnoses in CHD patients had the most three diagnoses of disease and with the most comorbidities, namely dyspepsia (20.6%) and diabetes mellitus (19.0%). The most widely used coronary heart therapy in inpatients at Imelda Workers' Hospital in Indonesia was SDN (12.7%) while the combination therapy was Clopidogrel and Concor (4.2%). Drug interactions in CHD patients were mostly nifedipine and atorvastatin with moderate levels.
References
H, O. Y. (2019). Perkembangan Terapi Intervensi Pada Penyakit Jantung Koroner. Surabaya: Airlannga University Press.
Johanis, I., Hinga, I. A. T., & Sir, A. B. (2020). Faktor Risiko Hipertensi, Merokok dan Usia terhadap Kejadian Penyakit Jantung Koroner pada Pasien di RSUD Prof. Dr. W. Z. Johannes Kupang. Media Kesehatan Masyarakat, 2(1). https://doi.org/https://doi.org/10.35508/mkm.v2i1.1954.
Kemenkes RI. (2017). Profil Penyakit Tidak Menular Tahun 2016. Jakarta: Kemenkes RI.
Khazanah, W., Mulyani, N. S., Ramadhaniah, R., & Rahma, C. S. N. (2019). Konsumsi Natrium Lemak Jenuh Dan Serat Berhubungan Dengan Kejadian Penyakit Jantung Koroner Di Rumah Sakit Dr. Zainoel Abidin, Banda Aceh. Jurnal Kesehatan, 7(1). https://doi.org/https://doi.org/10.25047/j-kes.v7i1.72.
Lestari, R. D., Dewi, R., & Sanuddin, M. (2020). Evaluasi Penggunaan Obat Pada Pasien Jantung Koroner Di Instalasi Rawat Inap RSUD Raden Mattaher Jambi. Journal Of Healtcare Technologi and Medicine, 6(1). https://jurnal.uui.ac.id/index.php/JHTM/article/view/665
Mala, S., Afiah, A. S. N., & Dunggio, M. S. (2019). Gambaran Profil Lipid Pada Penderita Penyakit Jantung Koroner Di Rumah Sakit Umum Daerah Dr. H. Chasan Boesoirie Ternate. Kieraha Medical Journal, 1(1).
Misinem. (2015). Determinan Sosial dan Individu sebagai Prediktor Penyakit Jantung Koroner pada Penderita Diabetes mellitus di RSUP Dr. Sardjito Yogyakarta. Yogyakarta: Universitas Gadjah Mada.
Nur’aini, Kuncoro, B., & Yanti, Y. (2019). Evaluasi Interaksi Obat Jantung Koroner Pada Pasien Rawat Inap Rumah Sakit Umum Kabupaten Tanggerang 2017. Jurnal Farmagazine, 6(1).
Riset Kesehatan Dasar (Riskesdas). (2018). Badan Penelitian dan Pengembangan Kesehatan Kementerian RI tahun 2018.
Rosjidi, & Nurhidayat. (2014). Buku Ajar Perawatan Cedera Kepala dan Stroke. Yogyakarta : Ardana Media.
S. H., R., L, A., C. E, W., Rees, B., Davies, K., & R. S, T. (2017). Psychological Interventions For Coronary Heart Disease. Cochrane Database of Systematic Reviews, 4(10.1002/14651858 CD0002902).
Suciana, Hengky, H. K., & Usman. (2021). Analisis Faktor Risiko Penyakit Jantung Korener Pada Penderita Diabetes Melitus Tipe 2 Di RSUD Andi Makkasau Kota Parepare. Jurnal Ilmiah Manusia Dan Kesehatan, 4(2). https://doi.org/https://doi.org/10.31850/makes.v4i2.612.
Suherwin, S. (2018). Hubungan Usia, Jenis Kelamin Dan Riwayat Penyakit Dengan Kejadian Penyakit Jantung Koroner Di Instalasi Gawat Darurat Rumahsakit Tk.II dr. AK. Gani Palembang Tahun 2016. Jurnal ‘Aisyiyah Medika, 1(Februari). https://doi.org/https://doi.org/10.36729/jam.v1i1.248.
Sutejo, I. R., Nurqistan, H. D., Rasyada, I., Yuniasih, N. N., Yuniar, A., & Ramadhani, R. (2016). Kandungan Fitoestrogen Ekstrak Etanolik Akar Rami (Boehmeria nivea) Menurunkan Kadar Kolesterol Tikus Yang Diovariektomi. Nurseline Journal, 1(1). https://media.neliti.com/media/publications/197130-ID-phytoesterogen-component-of-ethanolic-ro.pdf.
Tajudin, T., Nugroho, I. D. W., & Faradiba, V. (2020). Analisis Kombinasi Penggunaan Obat Pada Pasien Jantung Koroner (Coronary Heart Disease) Dengan Penyakit Penyerta Di Rumah Sakit X Cilacap Tahun 2019. Pharmaqueous: Jurnal Ilmiah Kefarmasian, 1(2). https://doi.org/https://doi.org/10.36760/jp.v1i2.111
Tjay, T. H., & Rahardja, K. (2017). Obat-Obat Penting “Khasiat, Kegunaan dan Efek Sampingnya.” Jakarta: IKAPI.
Zanchetti, A., Hansson, L., & Leonetti, G. (2002). Drug Interaction Classifiation. https://www.drugs.com/drug_interaction.
