COMPLIANCE WITH TAKING TUBERCULOSIS MEDICATION INDEPENDENTLY
DOI:
https://doi.org/10.52943/jikeperawatan.v11i2.1764Keywords:
Perceptions, Tuberculosis, Adherence, MedicationAbstract
Health is a state of well-being, physically, mentally, spiritually and socially that enables everyone to live a socially and economically productive life. Pulmonary tuberculosis is a global health problem that can impact productivity and quality of life. According to WHO, there are an estimated 1,020,000 new TB cases per year (399 per 100,000 population) with 100,000 deaths per year (41 per 100,000 population). Compliance of pulmonary tuberculosis patients in taking medication is key to the success of tuberculosis treatment. This study aimed to explore patients' perceptions of pulmonary tuberculosis and medication adherence. This study is a qualitative study with a phenomenological approach. Data were collected using in-depth interviews and then analyzed by content analysis. The informants in this study consisted of eight tuberculosis patients. The results of this study found three themes, namely (1) understanding of tuberculosis disease, (2) the impact of tuberculosis disease, (3) patients' perceptions of tuberculosis disease. It was concluded that a better understanding of tuberculosis disease and treatment adherence can contribute to treatment success. It is suggested that patients can be aware and encouraged to take medication regularly.
Downloads
References
Becerra ScD, M. C., Appleton ScM, S. C., Franke ScD, M. F., Chalco, K. R., Arteaga, F. B., Bayona, J., Murray, M., Atwood BA, S. S., & Mitnick ScD, C. D. (2011). Tuberculosis burden in households of patients with multidrug-resistant and extensively drug-resistant tuberculosis: a retrospective cohort study. https://doi.org/10.1016/S0140
Bonadonna, L. V., Saunders, M. J., Zegarra, R., Evans, C., Alegria-Flores, K., & Guio, H. (2017). Why wait? The social determinants underlying tuberculosis diagnostic delay. PLoS ONE, 12(9). https://doi.org/10.1371/journal.pone.0185018
Chang, K. C., Leung, C. C., Grosset, J., & Yew, W. W. (2011). Treatment of tuberculosis and optimal dosing schedules. In Thorax (Vol. 66, Issue 11, pp. 997–1007). BMJ Publishing Group. https://doi.org/10.1136/thx.2010.148585
Conradie, F., Diacon, A. H., Ngubane, N., Howell, P., Everitt, D., Crook, A. M., Mendel, C. M., Egizi, E., Moreira, J., Timm, J., McHugh, T. D., Wills, G. H., Bateson, A., Hunt, R., Van Niekerk, C., Li, M., Olugbosi, M., & Spigelman, M. (2020). Treatment of Highly Drug-Resistant Pulmonary Tuberculosis. New England Journal of Medicine, 382(10). https://doi.org/10.1056/nejmoa1901814
de Gijsel, D., & von Reyn, C. F. (2019). A Breath of Fresh Air: BCG Prevents Adult Pulmonary Tuberculosis. International Journal of Infectious Diseases, 80, S6–S8. https://doi.org/10.1016/j.ijid.2019.02.036
Dewi Kristini, T., Hamidah, R., Kesehatan Masyarakat, F., Muhammadiyah Semarang, U., & Kesehatan Provinsi Jawa Tengah, D. (n.d.). Potensi Penularan Tuberculosis Paru pada Anggota Keluarga Penderita. In Jurnal Kesehatan Masyarakat Indonesia (Vol. 15, Issue 1). https://jurnal.unimus.ac.id/index.php/jkmi,
Dewi Kristini, T., Hamidah, R., Kesehatan Masyarakat, F., Muhammadiyah Semarang, U., & Kesehatan Provinsi Jawa Tengah, D. (2020). Potensi penularan tuberculosis paru pada anggota keluarga penderita. In Jurnal Kesehatan Masyarakat Indonesia (Vol. 15, Issue 1). https://jurnal.unimus.ac.id/index.php/jkmi,
Fang, X. H., Dan, Y. L., Liu, J., Jun, L., Zhang, Z. P., Kan, X. H., Ma, D. C., & Wu, G. C. (2019a). Factors influencing completion of treatment among pulmonary tuberculosis patients. Patient Preference and Adherence, 13, 491–496. https://doi.org/10.2147/PPA.S198007
Fang, X. H., Dan, Y. L., Liu, J., Jun, L., Zhang, Z. P., Kan, X. H., Ma, D. C., & Wu, G. C. (2019b). Factors influencing completion of treatment among pulmonary tuberculosis patients. Patient Preference and Adherence, 13, 491–496. https://doi.org/10.2147/PPA.S198007
Feasey, H. R. A., Corbett, E. L., Nliwasa, M., Mair, L., Divala, T. H., Kamchedzera, W., Khundi, M. E., Burchett, H. E. D., Webb, E. L., Maheswaran, H., Squire, S. B., & MacPherson, P. (2021). Tuberculosis diagnosis cascade in Blantyre, Malawi: a prospective cohort study. BMC Infectious Diseases, 21(1). https://doi.org/10.1186/s12879-021-05860-y
Figueroa, C. A., Velásquez, M. C. B., Bernal, L. F. R., & Sánchez, A. I. M. (2017). Instrumentos y herramientas de evaluación sobre conocimientos de tuberculosis. Enfermeria Global, 16(4), 499–514. https://doi.org/10.6018/eglobal.16.4.262831
Friedena, T. R., & Sbarbarob, J. A. (2007a). Promoting adherence to treatment for tuberculosis: The importance of direct observation. In Bulletin of the World Health Organization (Vol. 85, Issue 5, pp. 407–409). https://doi.org/10.2471/BLT.06.038927
Friedena, T. R., & Sbarbarob, J. A. (2007b). Promoting adherence to treatment for tuberculosis: The importance of direct observation. In Bulletin of the World Health Organization (Vol. 85, Issue 5, pp. 407–409). https://doi.org/10.2471/BLT.06.038927
GLOBAL TUBERCULOSIS REPORT 2021. (2021). http://apps.who.int/bookorders.
Harausz, E. P., Garcia-Prats, A. J., Law, S., Schaaf, H. S., Kredo, T., Seddon, J. A., Menzies, D., Turkova, A., Achar, J., Amanullah, F., Barry, P., Becerra, M., Chan, E. D., Chan, P. C., Ioana Chiotan, D., Crossa, A., Drobac, P. C., Fairlie, L., Falzon, D., … Hesseling, A. C. (2018). Treatment and outcomes in children with multidrug-resistant tuberculosis: A systematic review and individual patient data meta-analysis. PLoS Medicine, 15(7). https://doi.org/10.1371/journal.pmed.1002591
Hayati, Y. S., Putri, V. A., & Lukitasari, M. (2020a). THE EFFECTIVENESS OF LUNG TUBERCULOSIS EDUCATIONAL VIDEO TO INCREASE KNOWLEDGE AND ATTITUDES OF MASKS USE IN FAMILIES LIVING WITH TUBERCULOSIS PATIENTS. Journal of Nursing Science Update (JNSU), 8(2), 129–134. https://doi.org/10.21776/ub.jik.2020.008.02.10
Hayati, Y. S., Putri, V. A., & Lukitasari, M. (2020b). The effectiveness of lung tuberculosis educational video to increase knowledge and attitudes of masks use in families living with tuberculosis patients. Jurnal Ilmu Keperawatan (Journal of Nursing Science), 8(2), 129–134. https://doi.org/10.21776/ub.jik.2020.008.02.10
Hogan, A. B., Jewell, B. L., Sherrard-Smith, E., Vesga, J. F., Watson, O. J., Whittaker, C., Hamlet, A., Smith, J. A., Winskill, P., Verity, R., Baguelin, M., Lees, J. A., Whittles, L. K., Ainslie, K. E. C., Bhatt, S., Boonyasiri, A., Brazeau, N. F., Cattarino, L., Cooper, L. V., … Hallett, T. B. (2020). Potential impact of the COVID-19 pandemic on HIV, tuberculosis, and malaria in low-income and middle-income countries: a modelling study. The Lancet Global Health, 8(9). https://doi.org/10.1016/S2214-109X(20)30288-6
Hoppe, L. E., Kettle, R., Eisenhut, M., & Abubakar, I. (2016). Tuberculosis-diagnosis, management, prevention, and control: Summary of updated NICE guidance. BMJ (Online), 352. https://doi.org/10.1136/bmj.h6747
Igwaran, A., & Edoamodu, C. E. (2021). Bibliometric analysis on tuberculosis and tuberculosis-related research trends in Africa: A decade-long study. Antibiotics, 10(4). https://doi.org/10.3390/antibiotics10040423
Juliasih, N. N., Mertaniasih, N. M., Hadi, C., Soedarsono, Sari, R. M., & Alfian, I. N. (2020). Factors affecting tuberculosis patients’ quality of life in Surabaya, Indonesia. Journal of Multidisciplinary Healthcare, 13, 1475–1480. https://doi.org/10.2147/JMDH.S274386
Karumbi, J., & Garner, P. (2015). Directly observed therapy for treating tuberculosis. In Cochrane Database of Systematic Reviews (Vol. 2015, Issue 5). John Wiley and Sons Ltd. https://doi.org/10.1002/14651858.CD003343.pub4
Kasibante, J., Rutakingirwa, M. K., Kagimu, E., Ssebambulidde, K., Ellis, J., Tugume, L., Mpoza, E., Cresswell, F., & Meya, D. B. (2020). Tuberculosis preventive therapy (TPT) to prevent tuberculosis co-infection among adults with HIV-associated cryptococcal meningitis: A clinician’s perspective. Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, 20. https://doi.org/10.1016/j.jctube.2020.100180
Kavanagh, M. M., Gostin, L. O., & Stephens, J. (2020). Tuberculosis, human rights, and law reform: Addressing the lack of progress in the global tuberculosis response. PLoS Medicine, 17(10). https://doi.org/10.1371/journal.pmed.1003324
Kemenkes. (2019). Data dan Informasi Profil Kesehatan Indonesia 2018.
Kemenkes RI. (2018). Kemenkes, Profil Kesehatan Indonesia 2017. Kementerian Kesehatan Republik Indonesia.
Kemenkes.(2017). (2017). Profil Kesehatan Indonesia 2017.
Kilale, A. M., Pantoja, A., Jani, B., Range, N., Ngowi, B. J., Makasi, C., Majaha, M., Manga, C. D., Haule, S., Wilfred, A., Hilary, P., Mahamba, V., Nkiligi, E., Muhandiki, W., Matechi, E., Mutayoba, B., Nishkiori, N., & Ershova, J. (2022a). Economic burden of tuberculosis in Tanzania: a national survey of costs faced by tuberculosis-affected households. BMC Public Health, 22(1). https://doi.org/10.1186/s12889-022-12987-3
Kilale, A. M., Pantoja, A., Jani, B., Range, N., Ngowi, B. J., Makasi, C., Majaha, M., Manga, C. D., Haule, S., Wilfred, A., Hilary, P., Mahamba, V., Nkiligi, E., Muhandiki, W., Matechi, E., Mutayoba, B., Nishkiori, N., & Ershova, J. (2022b). Economic burden of tuberculosis in Tanzania: a national survey of costs faced by tuberculosis-affected households. BMC Public Health, 22(1). https://doi.org/10.1186/s12889-022-12987-3
Kim, J. K., Jeong, I., Lee, J. Y., Kim, J. H., Han, A. Y., Kim, S. Y., & Joh, J. S. (2018a). Tuberculosis relief belt supporting project (tuberculosis patient management project for poverty group). Tuberculosis and Respiratory Diseases, 81(3), 241–246. https://doi.org/10.4046/trd.2017.0043
Kim, J. K., Jeong, I., Lee, J. Y., Kim, J. H., Han, A. Y., Kim, S. Y., & Joh, J. S. (2018b). Tuberculosis relief belt supporting project (tuberculosis patient management project for poverty group). Tuberculosis and Respiratory Diseases, 81(3), 241–246. https://doi.org/10.4046/trd.2017.0043
Koech, B. A., & Nyamboga, Dr. E. N. (2017). The role of communication in the management of tuberculosis disease. IOSR Journal of Humanities and Social Science, 22(05), 62–66. https://doi.org/10.9790/0837-2205066266
Law, S., Daftary, A., O’Donnell, M., Padayatchi, N., Calzavara, L., & Menzies, D. (2019). Interventions to improve retention-in-care and treatment adherence among patients with drug-resistant tuberculosis: A systematic review. European Respiratory Journal, 53(1). https://doi.org/10.1183/13993003.01030-2018
Lestari, A. P. Y., Kusumaningtiyas, D. P. H., & Priastana, I. K. A. (2021). FAMILY SOCIAL SUPPORT AND PATIENTS MOTIVATION PREVENT PULMONARY TUBERCULOSIS TRANSMISSION. Jurnal Riset Kesehatan, 10(1), 57–64. https://doi.org/10.31983/jrk.v10i1.6648
Lisum, K., Waluyo, A., & Nursasi, A. Y. (2021). Treatment Adherence among Tuberculosis patients: A Concept Analysis. Open Access Macedonian Journal of Medical Sciences, 9(T5), 20–28. https://doi.org/10.3889/oamjms.2021.7849
Lisum, K., Waluyo, A., Nursasi, A. Y., & Pasaribu, J. (2022). Youth perspective on pulmonary tuberculosis parent’s care. International Journal of Public Health Science, 11(3), 982–988. https://doi.org/10.11591/ijphs.v11i3.21398
Mccormick, C. L. (2017). GAPS OF TUBERCULOSIS: A REVIEW OF THE LITERATURE SURROUNDING THE DIAGNOSIS, PROGNOSIS, TREATMENT, AND PREVENTION OF TUBERCULOSIS.
Mukherjee, A., Kaeley, N., Dhar, M., Kumar, S., & Bhushan, B. (2019). Prevalence, characteristics, and predictors of tuberculosis associated anemia. Journal of Family Medicine and Primary Care, 8(7), 2445. https://doi.org/10.4103/jfmpc.jfmpc_311_19
Pradipta, I. S., Idrus, L. R., Probandari, A., Lestari, B. W., Diantini, A., Alffenaar, J. W. C., & Hak, E. (2021). Barriers and strategies to successful tuberculosis treatment in a high-burden tuberculosis setting: a qualitative study from the patient’s perspective. BMC Public Health, 21(1). https://doi.org/10.1186/s12889-021-12005-y
Pradipta, I. S., Idrus, L. R., Probandari, A., Puspitasari, I. M., Santoso, P., Alffenaar, J. W. C., & Hak, E. (2022). Barriers to Optimal Tuberculosis Treatment Services at Community Health Centers: A Qualitative Study From a High Prevalent Tuberculosis Country. Frontiers in Pharmacology, 13. https://doi.org/10.3389/fphar.2022.857783
Putra, K. W. R., & Toonsiri, C. (2019a). Factors related to the successful treatment of tuberculosis: A literature review. In Belitung Nursing Journal (Vol. 5, Issue 4, pp. 136–146). Belitung Raya Publisher - Belitung Raya Foundation. https://doi.org/10.33546/bnj.749
Putra, K. W. R., & Toonsiri, C. (2019b). FACTORS RELATED TO THE SUCCESSFUL TREATMENT OF TUBERCULOSIS: A LITERATURE REVIEW. Belitung Nursing Journal, 5(4), 136–146. https://doi.org/10.33546/bnj.749
Rem, B., & Fos, F. (2019a). Social incentives for adherence to tuberculosis treatment. In Rev Bras Enferm [Internet] (Vol. 72, Issue 5).
Rem, B., & Fos, F. (2019b). Social incentives for adherence to tuberculosis treatment. In Rev Bras Enferm [Internet] (Vol. 72, Issue 5).
Ridho, A., Alfian, S. D., van Boven, J. F. M., Levita, J., Yalcin, E. A., Le, L., Alffenaar, J. W., Hak, E., Abdulah, R., & Pradipta, I. S. (2022). Digital Health Technologies to Improve Medication Adherence and Treatment Outcomes in Patients With Tuberculosis: Systematic Review of Randomized Controlled Trials. In Journal of Medical Internet Research (Vol. 24, Issue 2). JMIR Publications Inc. https://doi.org/10.2196/33062
Rudgard, W. E., Evans, C. A., Sweeney, S., Wingfield, T., Lönnroth, K., Barreira, D., & Boccia, D. (2017). Comparison of two cash transfer strategies to prevent catastrophic costs for poor tuberculosis-affected households in low- and middle-income countries: An economic modelling study. PLoS Medicine, 14(11). https://doi.org/10.1371/journal.pmed.1002418
Safwat, T. M., Abdel Fattah, E. B., & Soliman, A. G. (2019a). Gender differences in pulmonary tuberculosis in Abbassia Chest Hospital. Egyptian Journal of Bronchology, 13(3), 408–415. https://doi.org/10.4103/ejb.ejb_97_18
Safwat, T. M., Abdel Fattah, E. B., & Soliman, A. G. (2019b). Gender differences in pulmonary tuberculosis in Abbassia Chest Hospital. Egyptian Journal of Bronchology, 13(3), 408–415. https://doi.org/10.4103/ejb.ejb_97_18
Samal, J., & Dehury, R. (2016). Role of families in tuberculosis care: A case study. Muller Journal of Medical Sciences and Research, 7(2), 150. https://doi.org/10.4103/0975-9727.185020
Sterling, T. R., Njie, G., Zenner, D., Cohn, D. L., Reves, R., Ahmed, A., Menzies, D., Horsburgh, C. R., Crane, C. M., Burgos, M., Lobue, P., Winston, C. A., & Belknap, R. (2020). Guidelines for the treatment of latent tuberculosis infection: Recommendations from the national tuberculosis controllers association and CDC, 2020. MMWR Recommendations and Reports, 69(1). https://doi.org/10.15585/mmwr.rr6901a1
Syahrul, S., Saleh, A., Syam, Y., Latif, A. I., & Amir, H. (2022). Factor related to self care among Pulmonary Tuberculosis patients. International Journal of Health Sciences, 1218–1229. https://doi.org/10.53730/ijhs.v6ns4.5932
Van Der Werf, M. J., Langendam, M. W., Huitric, E., & Manissero, D. (2012). Series “rational use of anti-tuberculosis drugs” - Knowledge of tuberculosis-treatment prescription of health workers: A systematic review. European Respiratory Journal, 39(5), 1248–1255. https://doi.org/10.1183/09031936.00125611
Varaine, F., Michael, M. D., Rich, L., Barrera-Cancedda, A. E., Keshavjee, S., Mitnick, C., Mukherjee, J., Peruski, A., Msf, S., Ardizzoni, E., Baert, S., Balkan, S., Day, K., Ducros, P., Ferlazzo, G., Ferreyra, C., Gale, M., Hepple, P., Henkens, M., … Laissu, E. (2014). Médecins Sans Frontières and Partners In Health. Tuberculosis: Practical guide for clinicians, nurses, laboratory technicians and medical auxiliaries. www.pih.org.
Volmink, J., & Garner, P. (2007). Directly observed therapy for treating tuberculosis. In Cochrane Database of Systematic Reviews (Issue 4). John Wiley and Sons Ltd. https://doi.org/10.1002/14651858.CD003343.pub3
WHO. (2021). Global tuberculosis report 2021. http://apps.who.int/bookorders.
World Health Organization. (2020a). Global tuberculosis report 2020. World Health Organization.
World Health Organization. (2020b). Global tuberculosis report 2020. World Health Organization.
Yin, X., Tu, X., Tong, Y., Yang, R., Wang, Y., Cao, S., Fan, H., Wang, F., Gong, Y., Yin, P., & Lu, Z. (2012). Development and Validation of a Tuberculosis Medication Adherence Scale. In PLoS ONE (Vol. 7, Issue 12). https://doi.org/10.1371/journal.pone.0050328
Yulianti Sutrisno, R., Rossytalia Widiyastuti, D., Wahyu Setyo Budi, A., Tesma Wulandari, B., Irawati, K., Suanrueang, P., & Author, C. (2022a). Patient Experience in The Healing Process of Tuberculosis: A Phenomenology Study. IJNP (Indonesian Journal of Nursing Practices, 6(1), 57–64. https://doi.org/10.18196/ijnp.v6i1.15662
Yulianti Sutrisno, R., Rossytalia Widiyastuti, D., Wahyu Setyo Budi, A., Tesma Wulandari, B., Irawati, K., Suanrueang, P., & Author, C. (2022b). Patient Experience in The Healing Process of Tuberculosis: A Phenomenology Study. IJNP (Indonesian Journal of Nursing Practices, 6(1), 57–64. https://doi.org/10.18196/ijnp.v6i1.15662
Zimmer, A. J., Klinton, J. S., Oga-Omenka, C., Heitkamp, P., Nawina Nyirenda, C., Furin, J., & Pai, M. (2022). Tuberculosis in times of COVID-19. Journal of Epidemiology and Community Health, 76(3). https://doi.org/10.1136/jech-2021-217529
Zuo, X., Dong, Z., Zhang, P., Zhang, P., Zhu, X., Qiao, C., Yang, Y., & Lou, P. (2022). Cognitive-behavioral therapy on psychological stress and quality of life in subjects with pulmonary tuberculosis: a community-based cluster randomized controlled trial. BMC Public Health, 22(1). https://doi.org/10.1186/s12889-022-14631-6
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Jurnal Ilmiah Keperawatan IMELDA

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.